Andrea Prader 1919–2001

Andrea Musacchio

refinements of this equipment. There was a direct analogy with the voltage clamp approach in nerve, but now length or force became the controlled parameter in place of voltage. This approach was applied in a quantitative study of the relation between the steady force produced by an active muscle fiber and its length: Huxley showed that force is proportional to overlap between the thick and thin...

Andrea Pimentel

SIR, We previously reported an autoinflammatory disease associated with nucleotide-binding oligomerization domain containing protein 2 (NOD2) gene mutations, designated as NOD2-associated autoinflammatory disease (NAID) [1, 2]. To date, none of the studies of NOD2 mutations have demonstrated spontaneous inflammation in NOD2-associated diseases [3]. Herein we report a patient with NAID to illust...

Andrea Rassell exegesis

33-36 Andrea Cariati.indd

Ogilvie syndrome, or acute colonic pseudo-obstruction, is a severe distension of the colon caused by decreased large bowel motility in the absence of a mechanical obstruction. It can be a consequence of medical treatment such as with clozapine. An 82-year-old male with Alzheimer disease under treatment with antipsychotics (clozapine) was admitted with abdominal distension and constipation. On e...

Profile of Andrea Rinaldo.

By 1985, Andrea Rinaldo was losing interest in fluid mechanics. The newly appointed full professor of hydrodynamics at Italy’s University of Trento had excelled in studying the intricacies of eddies, vortices, and fluid flow through porous media. But Rinaldo, lacking excitement, yearned for new avenues of research, seeking, he says, his road to Damascus. As part of his quest, Rinaldo attended a...